Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions
Sponsored by Al-Azhar University
About this trial
Last updated 10 months ago
Study ID
OPDEN-103-1-S
Status
Not yet recruiting
Type
Interventional
Phase
Early Phase 1
Placebo
No
Accepting
20 to 40 Years
All Sexes
Trial Timing
Started 8 months ago
What is this trial about?
This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated caries-affected dentin and the influence of Er, Cr: YSGG Laser treatment.
What are the participation requirements?
Inclusion Criteria
* o Patients aged (20 - 40) years.
* Presence of at least one posterior permanent molar with an occlusal carious lesion classified as ICDAS code 3 or 4 requiring operative treatment.
* Good general and oral health.
* Willingness to participate and provide informed consent.
Exclusion Criteria
* o Patients with systemic conditions affecting oral health or healing.
* Teeth with pulp involvement or periapical pathology.
* Allergy to study materials.
* Poor oral hygiene or periodontal disease in the target tooth region.