Tubeless VATS for Lung Cancer Surgery

Sponsored by The First Affiliated Hospital of Guangzhou Medical University

About this trial

Last updated 5 months ago

Study ID

GMU-TUBELESS-VATS-2025

Status

Completed

Type

Interventional

Phase

N/A

Placebo

Accepting

18 to 75 Years

All Sexes

Trial Timing

Ended 5 months ago

What is this trial about?

This prospective cohort study evaluates lung injury, long-term clinical outcomes, and environmental impacts of tubeless video-assisted thoracic surgery (VATS) compared with conventional intubated VATS for lung cancer resection. The study aims to determine whether the tubeless approach reduces anesthetic exposure, minimizes lung injury, enhances patient recovery, and decreases carbon emissions, contributing toward sustainable surgical practices.

What are the participation requirements?

Inclusion Criteria

1. Patients aged ≥18 years scheduled for elective video-assisted thoracic surgery (VATS) for confirmed or suspected lung cancer.

2. Clinical stage suitable for surgical resection (lobectomy, segmentectomy, or wedge resection).

3. American Society of Anesthesiologists (ASA) physical status classification ≤III.

4. Ability to understand and willingness to provide written informed consent.

5. Agreement to adhere to scheduled postoperative clinical follow-up assessments, including pulmonary function tests and survival status evaluations.

Exclusion Criteria

1. Patients requiring bilateral pulmonary procedures or planned open thoracotomy.

2. History of severe cardiopulmonary disease or unstable medical conditions that contraindicate minimally invasive thoracic surgery.

3. Emergency surgery due to acute respiratory or cardiovascular instability.

4. Inability to cooperate with the planned anesthetic and surgical protocols or postoperative follow-up procedures.

5. Pregnancy or lactation at the time of enrollment.

6. Known allergy or contraindication to anesthetic agents or materials used in the study.

7. Enrollment in another interventional clinical study within the past 30 days.