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The Effectiveness of Allogenic Mesenchymal Stem Cells Therapy on Hair Regrowth in Androgenetic Alopecia.

Sponsored by National Institute of Blood and Marrow Transplant (NIBMT), Pakistan

About this trial

Last updated a year ago

Study ID

AFBMTC-2024-MSC in Alopecia

Status

Enrolling by invitation

Type

Interventional

Phase

Phase 1

Placebo

No

Accepting

20 to 59 Years
Male

Trial Timing

Ended 9 months ago

What is this trial about?

The goal of this study is to learn if mesenchymal stem cell therapy (treatment group) can effectively treat adrogenic alopecia or male-pattern baldness, when compared to normal saline (given to placebo group). It will also assess the differences in patient satisfaction. The main focus will be to: 1. Compare the average hair regenerative effect of mesenchymal stem cells versus Placebo, in treatment of androgenetic alopecia. 2. To determine and compare the investigators assessment and patient satisfaction in both groups. Patients in treatment group will receive single session of MSC therapy injected in the scalp and placebo group will receive 0.9% saline solution. The participants will be followed for 12 weeks. The hair density and thickness will be mesured along with clinicians assessment and participant's satisfaction level.

What are the participation requirements?

Inclusion Criteria

* Male patients with AGA between age 25 to 59 years of age

* Clinical presentation consistent with Hamilton Norwood criteria grade ll to Vl

* Not currently receiving antiandrogens or minoxidil therapy.

Exclusion Criteria

* Patients with hair loss other than AGA

* Patients receiving 5-alpha reductase inhibitor or minoxidil therapy

* Patients who received PRP for at least 6 months prior to enrollment

* History of hypertrophic scars or bleeding disorders

* History of treatment with hyper or hypothyroidism