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To Compare the Consumption of Sevoflurane and Desflurane in Low Flow Anaesthesia

Sponsored by Rajiv Gandhi Cancer Institute & Research Center, India

About this trial

Last updated 2 years ago

Study ID

Res/SCM/23/2017/53

Status

Completed

Type

Observational

Placebo

No

Accepting

20 to 65 Years
All Sexes

Trial Timing

Ended 4 years ago

What is this trial about?

This prospective observational study aims to compare sevoflurane and Desflurane consumption in low-flow anaesthesia using the ASA (American Society of Anaesthesiology). Environmental Sustainability Committee recommendations. The patients aged 20-65 years, ASA I and II undergoing surgery under general anaesthesia were included in the study. Question: Can we reduce our carbon footprint of desflurane and sevoflurane using low-flow anaesthesia, according to the recommendations of the ASA Environment Sustainability Committee? PRIMARY To compare the mac hour consumption of sevoflurane and desflurane anaesthetic agents under low flow (one litre/min) conditions To calculate the carbon footprint of sevoflurane and desflurane in the study cases. SECONDARY To test whether a significant generation of carbon monoxide occurs due to the interaction of sevoflurane/desflurane with soda lime in the closed circuit Groups 1) low-flow sevoflurane (LFS)- 1 L/min gas flow 2) low- flow desflurane (LFD)- 1 L/min gas flow Anaesthesia will be administered according to the recommendations of the ASA Environment Sustainability Committee. Three strategies to reduce the fresh gas flow and environmental contamination are 1. Induction: Set the Vaporizer to Deliver a Concentration Greater than Intended 2. Intubation: Turn Off the Fresh Gas Flow, Not the Vaporizer. 3. Maintenance: Minimize Fresh Gas Flow During Maintenance.

What are the participation requirements?

Inclusion Criteria

1. Patients with American Society of Anesthesiologists grade (ASA) I & II.

2. Patients with age 20-65 years.

Exclusion Criteria

1. Contraindications to inhalation agents.

2. Liver dysfunction.

3. Chronic alcoholism.

4. Chronic smokers.