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Cohort Study on Biomarkers and Clinical Treatment of Tinnitus

Sponsored by Zhiwu Huang, Ph.D.

About this trial

Last updated 2 years ago

Study ID

SH9H-2022-T379-1

Status

Recruiting

Type

Interventional

Phase

N/A

Placebo

No

Accepting

18-75 Years
Up to 65 Years
All
All

Trial Timing

Ended 10 months ago

What is this trial about?

The goal of this clinical trial is to search for biomarkers in tinnitus patients in tinnitus patients and changes in biomarkers before and after treatment. The main questions it aims to answer are: - What are the biomarkers of tinnitus patients? - How do these biomarkers change during treatment and is there a good correlation with behavioral outcomes? Participants will be asked to complete audiological examination, tinnitus assessment, and magnetoencephalography examination, and they will receive sound therapy or repetitive transcranial magnetic stimulation therapy.

What are the participation requirements?

Yes

Inclusion Criteria

1. Subjective tinnitus lasting for more than 6 months, with a score of>36 of the Tinnitus Disability Inventory (THI);

2. The otoscopy examination showed that the ear canal and eardrum were normal, and the tympanic impedance maps of both ears were Type A, indicating that language ability met the requirements of language testing

No

Exclusion Criteria

1. Family or congenital deafness history, ototoxicity drug use history, otitis media patients, etc

2. Suffering from major physical diseases (sensory and motor disorders, neurological disorders, brain injuries, and other organic diseases) or mental disorders

3. The patient has aggressive behavior and an impulse to damage the device

4. Metal in the body (including orthodontics, dental implants), tattoos, and heart stent surgery

5. Having claustrophobia

6. Contraindications to magnetic resonance examination

Locations

Location

Status

Recruiting