Control of Emergence Blood Pressure During Craniotomy for Tumor Surgery Between Labetolol and Diltiazem
Sponsored by Mahidol University
About this trial
Last updated 12 years ago
Study ID
594/2552(EC4)
Status
Completed
Type
Interventional
Phase
Phase 1
Placebo
No
Accepting
18+ Years
All Sexes
Trial Timing
Ended 12 years ago
What is this trial about?
The purpose of this study is to determine the effectiveness of the antihypertensive drugs in the control of emergence blood pressure after tumor resection craniotomy; compared between labetalol (Avexa) and diltiazem (Herbessor).
Also the investigators seek to determine the effective dose of the antihypertensive drugs and their side effects in Thai population.
What are the participation requirements?
Inclusion Criteria
* patients who scheduled for craniotomy for tomor removal
Exclusion Criteria
* allergic to labetalol or diltiazem
* Bradycardia < 60 beat/min
* Second or third degree heart block
* Severe asthma or severe COPD
* Brain stem tumor